International Law for International Relations
Environment and Social Development
Intelligent Robot and Advanced Manufacturing
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Critical Conservation and Revitalization of Architecture Heritage
Curating Contemporary Art: Museums, Galleries, Exhibitions and the Curator
Artificial Intelligence and Big Data
Introduction to Computer Science and Programming
Basics of Machine Learning and Data Analysis
Smart Earth
Infections and Immune Response
Healthy China Initiative and International Health Cooperation
The Outline of《Infections and Immune Response》
Basic Teaching Information
Course Code:2030610013002 |
Course Title:Infections and Immune Response |
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Faculty:Basic Medical Sciences |
Targeted Student:in medical sciences, life sciences, pharmacy, public health, other related disciplines |
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Course Credit:1 |
Lecture Hours: (consisted of ___16__ theoretical hours and ___0__ practical hours) |
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Course Leader: |
Name:Yuchen Xia |
E-mail:yuchenxia@whu.edu.cn |
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Office:Room 407, Building 3, School of Basic Medical Sciences, Wuhan University |
Mobile: |
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Course Staff: |
Name:Shuliang Chen |
E-mail:chen-shuliang@whu.edu.cn |
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Office:Institute of Medical Virology, School of Basic Medical Sciences, Wuhan University |
Mobile: |
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Course Type:一般通识课程General Course |
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Related Preview Courses: None |
Course Introduction
Pathogens, including viruses, bacteria, fungi, and parasites, can cause severe health issues, and negative impacts on economic growth as well as social stability. This underscores the need for knowledge of infection mechanisms and their outcomes. Infections and Immune Response intends to introduce students in medical sciences, life sciences or other related disciplines to the variety of infections and immune responses in humans.
Weekly meetings will cover both classic and newly emerged infectious agents and diseases, including HBV, HIV, Coronavirus, tumor virus, Helicobacter pylori, malaria, schistosomiasis, Cryptosporidium and Cestode infection. Lectures will be given by experts in these areas from Wuhan University, Technical University of Munich (Germany), Cleveland Clinic Lerner College of Medicine (US), Natural History Museum (UK) and Rush University Medical Center (US), Korea Research Institute of Chemical Technology (Korea).
This course focuses on infectious agents and interactions with host immune responses and anti-infectives at the cellular and molecular level. It consists of three main sections. (1) Viral infections: areas covered include structure of pathogens, viral life cycle, pathogenesis and host immune responses, diagnosis and treatments. Topics will be selected to present important concepts in the context of infections or co-infections and host immune responses and/or major challenges in controlling infections. Recent advances in understanding virus-host interactions, host responses to infections, global control strategies and elimination strategies will be emphasized. (2) Bacterial infections: Helicobacter pylori will be considered as specific examples, and how does Helicobacter pylori infect digestive tract and modulate the composition of gastrointestinal microbiota will be discussed. (3) Parasitic diseases: this course will systematically introduce the mechanisms of infection, immune evasion strategies and pathogenesis. More insight will be given into parasite-host interactions, epigenetic gene regulation, and immune responses to parasites. The global challenges in the field of treatment and control strategies will be also discussed.
The Allocation of Content and Lecture Hours
Content |
Lecture Hours |
Past, present and future of viral hepatitis |
1.5 |
HIV infection and immune response |
1.5 |
Insight into the malaria parasite-host interaction |
1.5 |
Immune response in virus coinfection |
1.5 |
Cestode infection and human disease |
1.5 |
Coronavirus |
2 |
Mechanisms of host-pathogen interaction during chronic infection, inflammation and carcinogenesis |
1.5 |
HBV and HDV |
2 |
The global control and elimination of schistosomiasis |
1.5 |
Cryptosporidium infection and mucosal immunity |
1.5 |
Assessment Methods and Marking Criterion
Assessment 1 - Comprehensive evaluation
Weighting: 60%
Criterion: attendance and class performance (quizzes or online discussions)
Assessment 2 - Essay in the interplay between host and pathogen
Weighting: 40%
Length: no less than 1000 words
Textbooks and References
Principles of Molecular Virology, Alan J. Cann, 6th Edition, 2015
Principles and Practice of Infectious Diseases, John E. Bennett, Raphael Dolin and Martin J. Blaser, 8th Edition, 2015
Medical Immunology, Gabriel Virella, 7th Edition, 2020
Primary literature